Sakura Alien 2 contains three ending paths centered around Hiyori, Ena, or both girls together. The shared route is fairly linear, with the main branching decision happening at the very start of the game.
Harem Ending
Both of them.
Oh well. I wasn’t going to ignore her anyway.
The pretty woman I saw outside!
That’s kind of cute…
I don’t know. I don’t dislike seeing you.
I don’t really mind.
I’m fine. Don’t worry.
Kiss Professor Sakai.
Choose any option.
Choose any option.
Hiyori Ending
Hiyori.
Choose any option until finishing the game.
Ena Ending
Ena.
Choose any option until finishing the game.
